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  7. Karyopharm Therapeutics
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Karyopharm Therapeutics | Sustainability Performance

https://www.karyopharm.com
Linkedin

Karyopharm Therapeutics develops and commercializes cancer treatments, focusing on innovative drug therapies for hematologic malignancies and solid tumors.

2008

United States

201 - 500 employees

Pharmaceuticals

$100M - 500M in revenue

Not profitable

Submit or report inaccurate dataDownload Company Insights

Sustainability Ranking & Industry Benchmark

#5587
Overall
#1110
in United States
#118
in Pharmaceuticals

Sustainability Maturity

​​0123456789​​%

Sustainability Intent

Available in
Scale package

Access
​​0123456789​​%

Beyond Top 100

Overview
Governance
TargetsESG scores and Exclusions
Financial Data
Business performanceCapital & innovationAnalyst projections

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Market cap

32.0M $, 2026▼228.1% YoY

Revenue

146.0M $, 2025▲0.7% YoY

R&D intensity

85.62% 2025

Controversy level


Very Low
Low
Noticeable
High
Severe
Download Controversy Analysis
  • Karyopharm's cancer drug faced clinical efficacy debates in regulatory review.
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Market cap

32.0M $, 2026▼228.1% YoY

Revenue

146.0M $, FY2025▲0.7% YoY

EBITDA

-90.0M $, FY2025▼9.1% YoY

Operating margin

-62% Industry: -24▲48.6% YoY

Revenue & EBITDA

$146.0MFY2025 revenue

Total Annual
Revenue & EBITDA
($ B)

Annual revenue
EBITDA
3 year change
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Margin trends


Margin as % of revenue

Gross margin
Operating margin
Net margin

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Free cashflow

-127.6M 2024▲27.4% YoY

Capex

0.0 2024▼NaN% YoY

Debt/equity ratio

-0.8 Industry: 0▼NaN% YoY

R&D intensity

85.6%FY2025

R&D as % of revenue

Return on invested capital (ROIC)
Industry benchmark

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Return on invested capital

301.0%FY2026

Return on invested capital (ROIC)
Industry benchmark

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Analyst revenue estimates & actuals


Analyst consensus vs actuals
($ B)

Actual revenue
Consensus estimates
Estimate only

0.1

▼ 1.2%

2023

0.1

▼ 3.6%

2024

0.1

▼ 0.7%

2025

1.0

2030

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Environmental policy coverage

Carbon reduction policy

Not available

Human rights policy

Not available

Recycling policy

Not available

Workplace health & safety policy

Available

46%
Independent Directors

6 out of 13 incl. management

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Overall score

32

Environment

33

Social

47

Governance

15

Exclusion screening

Adult content

Not available

Alcoholic

Not available

Animal testing

Available

Firearms

Not available

Tobacco

Not available

Gambling

Not available

Nuclear

Not available

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Reporting

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Sustainability Report

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Sustainability employees



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