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  7. Ionis Pharmaceuticals
Company logo

Ionis Pharmaceuticals | Sustainability Performance

https://ionis.com/

Engages in the research and development of RNA-targeted therapeutics. Its pipeline addresses rare diseases, neurological conditions, and cardiovascular disorders. The company applies antisense technology to create treatments that regulate protein production, with several programs advancing through clinical trials.

1989

United States

1,001 - 5,000 employees

Biotechnology

$500M - 1B in revenue

Not profitable

Submit or report inaccurate dataDownload Company Insights

Sustainability Ranking & Industry Benchmark

#1867
Overall
#420
in United States
#28
in Biotechnology

Sustainability Maturity

​​0123456789​​%

Sustainability Intent

Available in
Scale package

Access
​​0123456789​​%

Industry Rank

139 out of 245

Overview
Environmental
Carbon emissionsEnergy consumptionWaste ManagementWater ManagementNature and biodiversityClimate risk
Social
Diversity and InclusionPay GapsHealth and SafetyExternalities
Governance
TargetsSDG ImpactESG scores and Exclusions
Financial Data
Business performanceCapital & innovationAnalyst projections

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Cumberland Pharmaceuticals

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Renewable energy

40% 2024
Aligned

Waste generated

590.0 tonnes, 2024
Aligned

Female employees

57% 2024
Leading

Externalities

729.1K $, 2024
Laggard

Market cap

11.7B $, 2026▼53.4% YoY

Revenue

943.0M $, 2025▼25.2% YoY

R&D intensity

97.03% 2025

Renewable energy

Reveal data for 1 credit
40%2024

Industry rank: 12 out of 245


Total energy consumption
and % renewables
(MWh, % of consumption)

Industry rank: 12 out of 245

Total energy

Share of renewable energy

Industry benchmark

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Renewable electricity

Reveal data for 1 credit
%2024

Industry rank: Beyond Top 100


Total electricity consumption
and % renewables
(MWh, % of consumption)

Industry rank: Beyond Top 100

Total electricity

Share of renewable electricity

Industry benchmark

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Intensity


Water consumption intensity (m³ /$M)
Industry Benchmark

72.4

B/M 101.4


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Female employees

Reveal data for 1 credit

Share of female employees (%)

25
50
75
100
Company
Benchmark
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Waste

Reveal data for 1 credit
590.02024

Total waste generated (tonnes)

Total waste
Recovered & recycled
Not-recovered & not-recycled
Industry Benchmark

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Controversy level


Very Low
Low
Noticeable
High
Severe
Download Controversy Analysis
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Carbon emissions breakdown

Reveal data for 2 credits

KPIMetricYear
20202021202220232024Benchmark
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Climate risk

OverallAcuteChronic
Reveal data for 20 credits
Unlock Acute & Chronic
18 assets assessed
ScenarioComing soon
68High
$642.7Bestimated revenue at risk
Thematic risk scoresESRS aligned scoresComing soon
Download Climate Risk AnalysisPowered by illuminem and GIST impact

Biodiversity loss in km²

Reveal data for 2 credits

Biodiversity loss in terms of the equivalent land affected (km²e)

Total biodiversity loss (km²e)
Industry benchmark
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Biodiversity loss in CO2e

Reveal data for 2 credits

Total biodiversity loss as CO2e tonnes

Total biodiversity loss (CO2e tonnes)
Industry benchmark

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Potential species loss

Reveal data for 2 credits

Estimated nature species lost due to corporate activity, expressed as Potentially Disappeared Fraction (PDF)

One row per year, with the latest at the top. Each driver uses its own scale.

Low ImpactHigh Impact
Industry benchmark
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Biodiversity impact

Reveal data for 2 credits

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20202021202220232024Benchmark
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PDF: Potentially Disappeared Fraction (of species) due to corporate activities

Waste management

Reveal data for 2 credits

KPIMetricYear
20202021202220232024Benchmark
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Water management

Reveal data for 2 credits

KPIMetricYear
20202021202220232024Benchmark
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Land use

Reveal data for 2 credits

KPIMetricYear
20202021202220232024Benchmark
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Diversity & inclusion

Reveal data for 3 credits

KPIMetricYear
20202021202220232024Benchmark
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Pay gap breakdown

Reveal data for 1 credit

KPIMetricYear
20202021202220232024Benchmark
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Health & safety

Reveal data for 2 credits

KPIMetricYear
20202021202220232024Benchmark
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Externalities

Reveal data for 1 credit

KPIMetricYear
20202021202220232024Benchmark
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Market cap

11.7B $, 2026▼53.4% YoY

Revenue

943.0M $, FY2025▼25.2% YoY

EBITDA

-381.0M $, FY2025▼9.1% YoY

Operating margin

-40% Industry: -8722▲66.6% YoY

P/E ratio

-33.2 Industry: 6▼65.3% YoY

Revenue & EBITDA

$943.0MFY2025 revenue

Total Annual
Revenue & EBITDA
($ B)

Annual revenue
EBITDA
3 year change
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Margin trends


Margin as % of revenue

Gross margin
Operating margin
Net margin

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Free cashflow

-320.0M 2025▲70.7% YoY

Capex

51.0M 2025▼11.8% YoY

Debt/equity ratio

4.8 Industry: 2▼NaN% YoY

R&D intensity

97.0%FY2025

R&D as % of revenue

Return on invested capital (ROIC)
Industry benchmark

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Return on invested capital

-14.0%FY2026

Return on invested capital (ROIC)
Industry benchmark

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Analyst revenue estimates & actuals


Analyst consensus vs actuals
($ B)

Actual revenue
Consensus estimates
Estimate only

0.8

▲ 21.3%

2023

0.7

▲ 11.7%

2024

0.9

▲ 3.0%

2025

4.3

2031

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Environmental policy coverage

Carbon reduction policy

Not available

Human rights policy

Not available

Recycling policy

Available

Workplace health & safety policy

Available

38%
Independent Directors

8 out of 21 incl. management

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Overall score

64

Environment

38

Social

99

Governance

55

Exclusion screening

Adult content

Not available

Alcoholic

Not available

Animal testing

Available

Firearms

Not available

Tobacco

Not available

Gambling

Not available

Nuclear

Not available

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SDG impact

Reveal data for 5 credits
2024

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SDG impact (historical)

Reveal data for 5 credits

KPIMetricYear
20192020202120222023Benchmark
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Reporting

sustainability report symbol

Sustainability Report

Available

Not committed to key sustainability initiatives

Sustainability employees


Total sustainability employees

4-6


    Available in
    Scale package

    Access
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